ASSOCIATION OF RISK FACTORS OF CEREBRAL PALSY – A MATCHED CASE CONTROL STUDY
DOI:
https://doi.org/10.15621/ijphy/2020/v7i2/661Keywords:
Cerebral palsy, perinatal, risk factors, spastic diplegia, birth asphyxia, low birth weight.Abstract
Background: Cerebral palsy (CP) is one of the leading causes of childhood disability worldwide. The exact etiology of CP is poorly understood, but many risk factors are related to problems during pregnancy, labor, and delivery. The age and sex-matched control study were done to evaluate the association of perinatal risk factors with the development of CP among children in a rural area.
Methods: The study was conducted in the Division of Physical Medicine and Rehabilitation (PMR). Seventy clinically diagnosed CP children as cases and 70 children without CP as controls were included. Information regarding perinatal risk factors was collected from the parents of the children. Data were collected and statistically analyzed by using the Mc-Nemar chi-square test.
Results: The study results suggested that children with male sex (53%) had a higher incidence of CP compared to female (47%) children. Spastic diplegia (60%) was the most common subtype of CP. The significant ‘p’ value (< 0.01) reveals that all the perinatal risk factors are associated with the development of CP.
Conclusion: This study concluded that spastic diplegia was the most common subtype of CP. The perinatal risk
factors such as preterm, low birth weight, birth asphyxia, and neonatal seizures had a significant association with the development of CP.
References
Alikor EA. Pediatric and Child Health in Tropical region 2nd edn. Owerri, Nigeria: African Educational Service, 2007; 72-75.
Centers for disease control and prevention. Data & statistics for cerebral palsy, prevalence and characteristics. Available at http://www.cdc.gov/ncbddd/cp/data.html. [Last cited June 2016].
Jones Kathy. Incidence of Cerebral palsy remains constant in India on Indian Health News. Available at http://www.medindia.net/news/incidence of cerebral palsy remains constant in India.
Nabanita Das , Gayatri Bezboruah, Indira Das. Study on the Clinical Profile of Patients with Cerebral Palsy. Journal of Dental and Medical Sciences 2016; 15(7):54-58.
Anant Ganpath Bendale, Sanjay Pundalik Baviskar. A study of clinical profile and factors associated with cerebral palsy in children at tertiary health care center. International Journal of Paediatrics 2017; 2(2):8-11.
Hussain R. Saadi, Rosnah sutan, Aqil M Dhaher, Serene A. Alshaham. Maternal and foetal risk factors of cerebral palsy among Iraqi children: A case control study. Journal of preventive medicine 2012; 2(3):350-358.
Stokes M. Neurological Physiotherapy. London: Mosby International Limited 1998; 75-77.
Sahu suvanand , S.K. Kapoor, V.F. Reddaiah, U. Singh, K.R. Sundara. Risk factors for cerebral palsy. Indian journal of Paediatrics 1997; 64(5):677-685.
Hai MSBA, Sarker RN, Akter A, Biswas P, Kundu GC, Mehedi MT. Determinants of cerebral palsy among under -5 children. Bangladesh Med journal 2015; 44(1):3-7.
R Frank, J Garfinkle, M Oskoui, MI Shevell. Clinical profile of children with cerebral palsy born term compared with late-and post term: a retrospective cohort study. International Journal of Obstetrics and Gynaecology 2017; 124(1):1738-1745.
Jan S. Tecklin. “Paediatric physical therapy”. Lippincott Willams & Wilkins, Fifth edition, 2014; 191-192.
Pless, I.B. The epidemiology of childhood disorders, cerebral palsy. Guilford Press, New York. 1994; 487-490.
Pschirrer ER, Yeomans ER, Does asphyxia cause cerebral palsy? Seminars in Perinatology 2000; 24(3):215-220.
Hagberg, B., Hagberg, G., Beckung, E., Uvebrant P. Changing panorama of cerebral palsy in Sweden. VIII. Prevalence and origin in the birth period 1991-94. Acta Paediatrica 2001; 90(3):271-277.
Singhi PD, Ray M, Suri G. Clinical spectrum of cerebral palsy in North India – an analysis of 1000 cases. Journal of Tropical Paediatrics 2002; 48(3):162-166.
Srivatsava V K, Laisram N, Srivatsava R K. Cerebral palsy. Indian Paediatrics 1992; 29(8):883-886.
Reddy B. A study of clinical spectrum and risk factors of cerebral palsy in children. Journal of Dental and Medical Sciences 2018; 17(1):49-52.
Suzan K. Campbell Irma J. Wilhelm, Darlene S. Slaton. Anthropometric characteristics of Young Children with Cerebral Palsy. Paediatric physical therapy 1989; 1(3):105-108.
Rajkumar, Anand Kumar Gupta, Ritesh Runu, Sanjay Kumar Pandey, Manish Kumar. Clinical profile of cerebral palsy: a study from multidisciplinary clinic at tertiary care centre. International Journal of Contemporary Paediatrics 2018; 5(4):1626-1630.
Mohan Makwana, Harish Kumar Mourya, Saroj Mourya, B. D. Gupta, Ratan Lal Bhati, Yogesh Garg. A clinic epidemiological study of cerebral palsy in western Rajasthan. International journal Contemp Pediatr 2017; 4(4):1146-1152.
Bottos M, Granato T, Allibrio G, Gioachin C and Puato ML. Prevalence of cerebral palsy in North-East Italy from 1965 to 1989. Developmental Medicine Child Neurology 1999; 41(1):26-39.
Kavcic A and Perat MV. Prevalence of Cerebral Palsy in Slovenia: Birth years 1981to 1990. Developmental Medicine Child Neurology 1998; 40(1):459-463.
Johnson A. Prevalence and Characteristics of Children with cerebral Palsy in Europe. Developmental Medicine Child Neurology 2002; 44(1); 633-640.
Gowda VK, Kumar A, Shivappa SK, Srikanteswara PK, Shivananda, Mahadeviah MS, Govindraj M, Ramaswamy P. Clinical profile, predisposing factors, and associated co-morbidities of children with Cerebral palsy in south India. Journal of paediatric Neuroscience 2015; 10(2):108-113.
Wilcox AJ, Russell IT. Birthweight and perinatal mortality: On weight –specific mortality. International Journal of Epidemiology 1983; 12(1):319-325.
Ozturk A., Dimeric, F., Yavuz, T, Yildiz, S., Degirmenci, Y., Dosoglu, M. and Avsar. Y. Antenatal and delivery risk factors and prevalence of cerebral pansy in Duzce (Turkey). Brain and development 2006; 29(1):39-42.
Erkin, G., Delialioglu, S. U., Ozel, S., Culha, C and Sirzai, H. Risk factors and clinical profiles in Turkish children with cerebral palsy, analyses of 625 cases. International Journal of Rehabilitation Research 2007; 31(1):89-91.
Lagunju IA, Fatunde OJ. Child with cerebral palsy in a developing country- diagnosis and beyond. Journal of Pediatric Neurology 2009; 7(1): 375-379.
Published
PDF Downloads: 709
How to Cite
Issue
Section
Copyright © Author(s) retain the copyright of this article.